World’s First Successful Bladder Transplant Gives New Life to Kidney Patient

 Here is the full English translation of the article:


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**On May 4, 2025, in Los Angeles, USA, the world’s first successful bladder transplant was performed.** Through this groundbreaking surgery, 41-year-old Oscar Larenza was given a new lease on life. Oscar had been suffering from cancer and kidney disease and had depended on dialysis for the past seven years, as both of his kidneys and most of his bladder had been damaged beyond repair.


In this pioneering operation, doctors transplanted a kidney and a bladder simultaneously from a deceased donor into Oscar’s body. The entire surgery lasted eight hours, and the new kidney began functioning immediately. Urine also started to collect properly in the new bladder, which meant Oscar no longer needed dialysis.


The surgery was led by Dr. Nima Nassiri (UCLA) and Dr. Inderbir Gill (USC). They had been preparing for more than four years, practicing on cadavers and animal models. Previously, when the bladder was damaged, surgeons had to construct an alternative using intestinal tissue—a method that involved significant risks. This new bladder transplant approach is expected to be considerably safer and more effective.


Although the long-term impacts of the transplant and the effects of immunosuppressive medications are still being monitored, Oscar’s recovery has given doctors great hope. Based on this success, a few more transplants will be conducted as part of clinical trial.

(Reference - CNN Health. (2025, May 4). World’s first bladder transplant performed in Los Angeles).

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